Egg quality & Embryo | Dr Rama Sofat Hospital
As you age, the DNA inside your eggs begins to degrade.
Because our eggs have been with us since before we were born,
they’re exposed to all sorts of damaging, but mostly unavoidable,
influences throughout our lives: fevers, infections, stress, toxins,
free radicals. And because human cells, including eggs, are fragile,
this exposure can lead to little “mistakes” in our egg cells’ DNA, called chromosomal abnormalities as explained Dr Rama Sofat
.
Fertility and egg quality are directly connected.
Women’s ovaries are naturally programmed to allow just one egg to grow, mature, and be released (“ovulated”) each cycles (usually each month). That one egg represents the one chance for pregnancy in that particular menstrual cycle.
That egg ovulated may be either normal or abnormal. If it’s normal, great—you have a healthy pregnancy. But if it’s not? Abnormal egg cells typically don’t fertilize or implant in the uterus, but in the rare case they do, they can result in miscarriage or genetic disorders like Down syndrome.
The difference in egg quality between a 25-year-old and a 40-year-old is a matter of the statistical likelihood of the one egg she’s
ovulated being normal.
Because women in their late 30s and 40s have a higher percentage of abnormal eggs, it’s much more likely that their one egg each month will be abnormal. That’s why natural fertility declines with age, and why we see infertility, miscarriage, and genetic disorders more often with women over 35.
When receiving a report of “poor embryo quality” the first inclination is often to point an accusatory finger at the embryology laboratory.
This is grossly unfair because the truth of the matter is that while the In Vitro Fertilization (IVF) embryology laboratory plays a pivotal role in the success of an In Vitro Fertilization (IVF) program, it is the IVF doctor that selects the ovarian protocol that drives egg development and, regardless of expertise, no embryologist can make “poor quality eggs” develop into “good quality embryos”.
As you age, the DNA inside your eggs begins to degrade.
Because our eggs have been with us since before we were born,
they’re exposed to all sorts of damaging, but mostly unavoidable,
influences throughout our lives: fevers, infections, stress, toxins,
free radicals. And because human cells, including eggs, are fragile,
this exposure can lead to little “mistakes” in our egg cells’ DNA, called chromosomal abnormalities as explained Dr Rama Sofat
.
Fertility and egg quality are directly connected.
Women’s ovaries are naturally programmed to allow just one egg to grow, mature, and be released (“ovulated”) each cycles (usually each month). That one egg represents the one chance for pregnancy in that particular menstrual cycle.
That egg ovulated may be either normal or abnormal. If it’s normal, great—you have a healthy pregnancy. But if it’s not? Abnormal egg cells typically don’t fertilize or implant in the uterus, but in the rare case they do, they can result in miscarriage or genetic disorders like Down syndrome.
The difference in egg quality between a 25-year-old and a 40-year-old is a matter of the statistical likelihood of the one egg she’s
ovulated being normal.
Because women in their late 30s and 40s have a higher percentage of abnormal eggs, it’s much more likely that their one egg each month will be abnormal. That’s why natural fertility declines with age, and why we see infertility, miscarriage, and genetic disorders more often with women over 35.
When receiving a report of “poor embryo quality” the first inclination is often to point an accusatory finger at the embryology laboratory.
This is grossly unfair because the truth of the matter is that while the In Vitro Fertilization (IVF) embryology laboratory plays a pivotal role in the success of an In Vitro Fertilization (IVF) program, it is the IVF doctor that selects the ovarian protocol that drives egg development and, regardless of expertise, no embryologist can make “poor quality eggs” develop into “good quality embryos”.
Egg quality & Embryo | Dr Rama Sofat Hospital
Reviewed by Amanpreet Singh
on
12:28 PM
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